anipamil
- Product Name
- anipamil
- CAS No.
- 83200-10-6
- Chemical Name
- anipamil
- Synonyms
- anipamil;Anipamilum [Latin];anipamil USP/EP/BP;2-Dodecyl-5-[3-methoxyphenethyl(methyl)amino]-2-(3-methoxyphenyl)pentanenitrile;2-(3-methoxyphenyl)-2-[3-[2-(3-methoxyphenyl)ethyl-methylamino]propyl]tetradecanenitrile;Benzeneacetonitrile, α-dodecyl-3-methoxy-α-[3-[[2-(3-methoxyphenyl)ethyl]methylamino]propyl]-
- CBNumber
- CB3884252
- Molecular Formula
- C34H52N2O2
- Formula Weight
- 520.79
- MOL File
- 83200-10-6.mol
anipamil Property
- storage temp.
- Store at -20°C
- solubility
- Acetone (Slightly), Methanol (Slightly)
- form
- Thick Oil to Gel
- color
- Pale Yellow
N-Bromosuccinimide Price
- Product number
- A672700
- Product name
- Anipamil
- Packaging
- 10mg
- Price
- $165
- Updated
- 2021/12/16
- Product number
- A672700
- Product name
- Anipamil
- Packaging
- 100mg
- Price
- $1320
- Updated
- 2021/12/16
- Product number
- API0010715
- Product name
- ANIPAMIL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.47
- Updated
- 2021/12/16
anipamil Chemical Properties,Usage,Production
Originator
Anipamil,Onbio Inc.
Uses
A long-acting analog of Verapamil (V125000) with antiarrhythmic and antihypertensive activity.
Manufacturing Process
1,7-Bis-(3-ethoxyphenyl)-3-methylaza-7-cyano-nonadecane:
0.06 mole of 1-cyano-1-(3-methoxyphenyl)tridecane (prepared by phase
transfer-catalyzed alkylation of 3-methoxyphenylacetonitrile with 1-
bromododecane) and 0.06 mole of 1-chloro-4-methylaza-6-(3-
methoxyphenyl)hexane [prepared from N-methyl-β-(3-
methoxyphenyl)ethylamine and 1-bromo-3-chloropropane by a method similar
to that described in Arzneim.-Forsch. 28 (II) (1978), 2048] were dissolved in
100 ml of dry toluene in a three-necked flask provided with a stirrer, dropping
funnel, reflux condenser and thermometer. 9.3 g (0.07 mole) of a 30%
strength suspension of sodium amide in toluene were then added dropwise at
from 100° to 110°C, with stirring, and stirring was continued under reflux for
a further 90 minutes.
The resulting reaction solution was poured into 200 ml of ice water, and the
toluene phase was separated off and washed twice with water. The required
amount of hydrochloric acid was added to the toluene solution, the toluene
was distilled off under reduced pressure and the residue, which remained was
recrystallized from acetone to give 1,7-bis-(2-methoxyphenyl)-3-methylaza-7-
cyanononadecane hydrochloride or α-dodecyl-3-methoxy-α-[3-[[2-(3-
methoxyphenyl)ethyl]methylamino]propyl]benzene-acetonitrile (anipamil);
MP: 60°-69.5°C.
Therapeutic Function
Coronary vasodilator, Antihypertensive
anipamil Preparation Products And Raw materials
Raw materials
Preparation Products
anipamil Suppliers
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 19892
- Advantage
- 58
View Lastest Price from anipamil manufacturers
- Product
- Anipamil 83200-10-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 500 MT
- Release date
- 2020-05-11